After a frustrating few hours trying to figure out why my Print Screen prt sc button on my Vista laptop keyboard would not work, I figure it may help to post what I found here:

In order for the print screen button to work, the FN button and the print screen button must be depressed at the same time. The Fn button is located beside the Windows logo ( bottom right hand corner).

You can also use the Print screen function by doing the following: Click on Start , then All Programs , Accessories, Ease of Access , On Screen keyboard , then Prt Screen.

The best- IMO- is the Snipping Tool. To find this, type Snipping Tool in the search bar. It walks you through the process.