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Trends in Prescription Drug Spending, 2016-2021 (PDF)
Assistant Secretary for Planning and Evaluation [ASPE], U.S. Department of Health and Human Services [HHS] Link to more items from this source
Sept. 30, 2022

13 pages. "In 2021, the U.S. health care system spent $603 billion on prescription drugs, before accounting for rebates, of which $421 billion was on retail drugs. Spending growth on drugs was largely due to growth in spending per prescription, and to a lesser extent by increased utilization (i.e., more prescriptions). Expenditure growth was larger for non-retail drug expenditures (25%) than for retail expenditures (13%).... Drug spending is heavily driven by a relatively small number of high-cost products."

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